Construction was started on the C. H. Moore Homestead by John and Minerva Moore Bishop. Mr. Bishop was a prosperous grain and lumber dealer in Clinton. Work on the C. H. Moore Homestead was completed in 1867 after the Civil War had ended and life took on a more normal pattern. Soon after this, the Bishops lost their only child. After Minerva Bishop's death in the early 1880's, Mr. Bishop sold the house to his brother-in-law, Clifton H. Moore.